Atopic Dermatitis, a Package with Thousands Surprises
نویسنده
چکیده
The biological activity of (PEDF, (molecular weight ~45 kDa) includes the modulation of the activity of Vascular Endothelial Growth Factor (VEGF). The expression of PEDF and VEGF within both the retina and RPE is relevant to this study [1,2-9]. Any immunologic inhibition of the influence of PEDF over VEGF might result in a loss of control over the activity of VEGF. Without this restraint VEGF could overact leading to the excessive blood vessel propagations typical of several ocular diseases that involve uncontrolled vascular proliferation [10].
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